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美國(guó)Affymetrix Panomics
2008年Affymetrix收購(gòu)Panomics
Panomics Inc.是一家致力于平行定量生物學(xué)(PQB)領(lǐng)域的生命科學(xué)公司,位于美國(guó)硅谷。產(chǎn)品主要應(yīng)用于細(xì)胞信號(hào)轉(zhuǎn)導(dǎo)、RNA干擾調(diào)控的基因沉默、生物標(biāo)志物的發(fā)現(xiàn)、預(yù)測(cè)毒理學(xué)和轉(zhuǎn)錄調(diào)控等研究領(lǐng)域,Panomics Inc.旨在成為生命科學(xué)研究、臨床研究、藥物發(fā)現(xiàn)等研究領(lǐng)域的領(lǐng)先者。
Panomics公司的QuantiGene2.0 產(chǎn)品是基于Branched DNA(b-DNA)技術(shù),完成核酸水平的精確定量檢測(cè)。它克服了傳統(tǒng)的real-time PCR(或者q-PCR)技術(shù)中的種種缺陷與不確定因素,無(wú)需抽提純化RNA,無(wú)需反轉(zhuǎn)錄,無(wú)需PCR擴(kuò)增,對(duì)樣本量下限無(wú)要求(只需mRNA拷貝數(shù)在檢測(cè)范圍內(nèi)),只需將樣本用特定裂解液裂解后,經(jīng)探針雜交與信號(hào)放大即可迅速得到比real-time PCR更加精確的定量結(jié)果。除組織、細(xì)胞樣本外,該技術(shù)對(duì)血液樣本與福爾馬林浸泡、石蠟包埋切片(FFPE)同樣具有極高的精確度、準(zhǔn)確性與重現(xiàn)性。
Affymetrix Completes Acquisition of Panomics
Panomics now part of Affymetrix, is still focused on delivering innovative solutions for Parallel Quantitative Biology or PQB.
What is PQB? We define PQB as contextual, systems-level measurements of genes, proteins and their cellular functions. PQB will facilitate understanding of biological pathways and networks in the context of normal physiology and development, disease pathology and drug treatment.
Our mission is to establish worldwide leadership with PQB products for basic life science research, clinical research, and drug discovery and development based on innovative solutions for critical applications such as cell signaling, RNAi-mediated gene silencing and high information assays, clinical biomarker discovery, predictive toxicology and transcription regulation.